"The relationship between traumatic brain injury and fracture healing is poorly understood. Patients with traumatic brain injury have been shown to heal fractures faster and form more callus; however, the underlying mechanisms are largely unknown. Our project will examine the role of plasma leptin in accelerated fracture healing associated with traumatic brain injury. Radiographic healing and plasma leptin levels will be compared between patients with and without traumatic brain injury in the context of tibial or femoral shaft fractures. The findings of this study will shed light on the relationship between traumatic brain injury and fracture healing and may identify potential targets for novel therapeutic agents. I am very thankful for the OTA’s support through the Resident Research Grant. This grant will provide essential funding for our project."
Gareth Ryan, University of Calgary, Calgary, AB
Supervisor: Dr. Prism Schneider